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Hydroxyapatite

Microbiome Friendly

Fluoride Free

"Hydroxyapatite has been studied in lab and clinical settings for its role in enamel remineralisation. That’s why I often suggest sticking with it for at least 3 months to build a consistent routine."

Dr Seb Lomas - Biological Dentist

Vegan Trending

Gutology Hydroxyapatite Toothpaste 120ml

£16.00

A fluoride-free toothpaste formulated with biomimetic hydroxyapatite a mineral that mirrors what’s naturally found in your teeth. It delivers a fresh, clean feel without harsh additives to support your natural microbiome

Gutology Toothpaste is fluoride-free, microbiome-friendly and made with natural ingredients without the synthetic surfactants or preservatives found in many mainstream formulas. Formulated with clinically studied ingredients that support the oral ecosystem.

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Hydroxyapatite is backed by clinical and laboratory research showing how it can bind to enamel surfaces and support remineralisation. Some studies have observed visible improvements after 8 weeks of consistent use especially in early enamel wear.

In laboratory studies, biomimetic hydroxyapatite has been shown to fill exposed dentin tubules (the microscopic channels in enamel that are associated with sensitivity) helping to form a protective mineral layer.

Yes, best for ages 3+ as the mint taste could be strong for little ones.

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Dr Seb Lomas - Biological Dentist

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Yes, best for ages 3+ as the mint taste could be strong for little ones.

Remineralising

Anti-Plaque

Supports Enamel

Biome Friendly

Antimicrobial

Remineralising

Anti-Plaque

Supports Enamel

Why replace your current toothpaste?

You swallow a whole tube of toothpaste every year. Is yours safe to swallow?

Microbiome-friendly

Supports a natural oral microbiome with ingredients you can use everyday.
Helps Rebuild Enamel Surface

Formulated with natural hydroxyapatite a biomimetic mineral shown in lab studies to restore enamel-like surfaces by replenishing calcium and phosphate.
No fluoride. No compromise.

Powered by clinically studied ingredients designed to support enamel strength and oral microbiome balance, without unnecessary additives.
No Harsh Ingredients

Free from SLS and aggressive surfactants. Formulated to support your oral microbiome - never disrupt it.
Fresh breath starts with balance

Your oral microbiome plays a key role in how your breath smells. Supporting that ecosystem helps you feel fresher, without masking.
The Oral-Gut Connection

Your mouth is the gateway to your microbiome. Brushing isn’t just cosmetic it’s a daily ritual that supports the balance your body depends on.

What’s in our toothpaste (and what isn’t)

Many are rethinking traditional formulas not just because of fluoride, but due to ingredients like SLS, parabens, and foaming agents.

Gutology Mineral Toothpaste is formulated without these, using clinically considered alternatives that support the oral microbiome, without disrupting it.

Microbiome-Focused Oral Care

Your mouth is home to a thriving ecosystem of bacteria your oral microbiome.

Gutology Toothpaste is powered by TrueBiotic®, a postbiotic derived from Lactobacillus plantarum HEAL19 and studied for its role in supporting microbial balance.

In lab studies, TrueBiotic® has been shown to:
• Help reduce IL-1β (an inflammation marker) in immune cell models
• Support beneficial bacteria in oral microbiome simulations
• Encourage microbial diversity in preclinical settings

Our fluoride-free formula is designed to work in harmony with your mouth’s natural ecology for a fresher, more balanced start to your day.

The Power of Hydroxyapatite

Hydroxyapatite is a biocompatible mineral that closely reflects the natural structure of enamel.

It helps support a more balanced, mineral-rich surface environment without disrupting the oral microbiome.

Sometimes, science feels a little like magic.

This is more than just cleaning

Gutology Mineral Toothpaste cleans your teeth effectively with a microbiome-friendly formulation.

Gut-Friendly

Protect your microbiome.
Cancel Anytime

No contracts, cancel anytime.
Free Shipping

Free shipping with your monthly order.
Sustain

Long-term oral protection.

Hydroxyapatite

Microbiome Friendly

Fluoride Free

Dr Seb Lomas - Biological Dentist

Vegan Trending

Gutology Hydroxyapatite Toothpaste 120ml

£16.00

The fluoride-free toothpaste formulated with biomimetic hydroxyapatite a mineral that mirrors what’s naturally found in your teeth. It delivers a fresh, clean feel without harsh additives to support your natural microbiome

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Yes, best for ages 3+ as the mint taste could be strong for little ones.

Buy Once

Subscribe & Save

Cancel Anytime
Adjust Delivery Frequency
Free Shipping

Delivery every 3 months

Delivery every 6 months

Delivery every 1 month

Dr Seb Lomas - Biological Dentist

Biomimetic hydroxyapatite is a biocompatible mineral that reflects the natural composition of tooth enamel. It helps to remineralise and protect, while supporting a balanced oral environment

Yes, best for ages 3+ as the mint taste could be strong for little ones.

Ingredients

GLYCERIN
AQUA
HYDRATED SILICA
HYDROXYAPATITE
GLYCOLIPIDS
XYLITOLNatural sweetener
LACTOBACILLUS FERMENTDerived from Lactobacillus Plantarum HEAL19
CELLULOSE GUM
CALCIUM CARBONATE
MENTHA ARVENSIS LEAF OIL
STEVIOSIDE
MENTHOL
ACACIA SENEGAL GUM
AROMA
MENTHA PIPERITA OIL
EUCALYPTUS OIL
LIMONENE

Directions

Simply use Gutology Toothpaste like your normal toothpaste, twice daily.

Frequently Asked Questions

Have concerns? That’s okay. You can find all your urgent answers right here.

Is this toothpaste worth the price?

Absolutely and here’s why:

At 120ml, Gutology’s toothpaste is significantly bigger than many leading natural alternatives, which often come in 75ml tubes. That means more value per use.

We use biomimetic hydroxyapatite a fluoride-free mineral that mirrors the natural structure of enamel and is studied for its role in supporting surface mineral balance.

Stick with it and save. Our subscription model rewards consistency with better pricing no commitment, cancel anytime.

Is this toothpaste suitable for children?

Yes! Gutology toothpaste is 100% safe for children, thanks to its gentle, fluoride-free formulation. Instead of fluoride, we use biomimetic hydroxyapatite — a clinically proven mineral that helps rebuild and protect tooth enamel, without any risk if swallowed.

It’s also free from harsh foaming agents (like SLS), artificial sweeteners, and synthetic preservatives, making it ideal for growing smiles and sensitive mouths.

For little ones, we also offer a naturally flavoured strawberry version — making brushing time a whole lot easier (and tastier).

Do you test for heavy metals?

Your health is our priority. Every batch is independently tested for heavy metals usingICP-MS (Inductively Coupled Plasma Mass Spectrometry)— one of the most advanced and sensitive detection methods available.
We test for critical elements includinglead, arsenic, mercury, and cadmium, all of which are consistentlybelow detectable limits.
We also screen for other trace elements such asnickel, chromium, cobalt, and zinc— and confirm that all results fallwell within the EU and UK’s strict safety thresholds for daily exposure.
These results are reviewed by our quality team to ensure the highest standards of purity and safety.

Is this product vegan and cruelty-free?

Yes, this has been requested by many nutritionists that we work with. We've achieved this by using a vegetable sourced glycerine in our formulation. It is also 100% cruelty-free.

What if I need more help?

We understand that digestive issues can be complex, that's why we offer a £75 voucher towards advanced microbiome testing to every DigestBox customer.

Allergies

You are responsible for carefully reading any ingredients listed on our website and/or on any packaging, labels and/or leaflets to avoid the risk of allergic or other adverse reactions.

For more information on allergies: click here.

Great!!

Love the product. after using for a few months, teeth feel great. My only suggestion is to offer a 100ml size for frequent travelers with carry on baggage. Thanks.

Ordered again once trial sample had run out. Im out of gutology toothepaste at the moment so have been using regular the last few days. Theres a very noticible difference in the taste and feel of my mouth now and I dont like it, cant wait for the new order to arrive.

Teeth become whiter, smoother, gums feel healthy too.
No artificial aftertaste!
I gave one away and he noticed his teeth got whiter.

Notice a change

I suffer from sensitivity - and since I started using Gutology I have notice a reduction and it only took a few weeks to notice. I am really pleased I chose to buy some because I kept putting it off because I was unsure, so I can confirm it really works well, love it. thank you.

So far so good

I havnt been using this toothpaste long but happy so far! Teeth seem whiter and cleaner than before! I have sensitive teeth with almost no enamel on the back from childhood food intolerances that gave me acid reflux along with other teeth issues from younger years, but my sensitivity has been so much less than, almost none existent at times! I have even been eating oranges again as they hurt to much the last couple of years. All could change but it’s only been two weeks and so far I’m more than happy! I didn’t know if to trust the reviews but gave it a try as I’m all for trying less toxic products and already a huge avocation on the importance of the micro biome! Will review again with an update when we get the next tubes I’m sure! Kids seem happy with the strawberry one also, well the youngest.. my eldest has the same as me and his dad.. anyway would recommend atleast trying it, worth the money atleast it was for me!

No more sickening foam!

At long last, a toothpaste that doesn’t have the sickening foam that has made me gag for as long as I can remember. Also, my mouth and tongue feels cleaner.

Can I ask if there will be a clove flavoured toothpaste but more so a mouthwash created? Sometimes, I’d like the option as I can find mint a bit sickening sometimes.

Also, I don’t feel my stomach playing up after brushing with this toothpaste. I don’t think I could go back to regular toothpaste now. The price is a lot for many but the health benefits are great and we can all make the product last longer if we have to, due to the price.

Thanks for creating this and keeping it a clean product.

Toothpaste

Finally found a great toothpaste that doesn’t hurt my gums . Meaning it doesn’t sting great product shall continue to use . Many thanks highly recommend .

excellent product.

I was really impressed with this tooth paste. it does everything a toothpaste should. It leaves teeth feeling clean and smooth without an overpowering taste and no mad foaming. my whole mouth feel happier if that possible! I am recommending it to my family and friends.

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Reviews in Other Languages

Tastes great

Tastes great. Nice clean feeling. No idea if it actually does what it says but i feel better buying consciously.

I’m very happy with this toothpaste I have only been using it for a month however the difference in my teeth is amazing definitely ordering a second tube..
Taste is good too..

Tastes delicious!

1 2 3

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Gutology Hydroxyapatite Toothpaste 120ml